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Product Detail |
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| Full Name： | Human connective tissue growth factor ELISA Kit | | | Shortened Name： | Human CTGF ELISA Kit |  | | Cat. | E0010h | | Packing： | 96T | | Price： | $ 736 | | Manual： |  | | Release date: | 2008 | | Category: | Cytokine | | User Operation: |  | | Product description: | 【 Font: Large Medium Small 】 | Intended use
This immunoassay kit allows for the in vitro quantitative determination of human
connective tissue growth factor,CTGF concentrations in cell culture supernates, serum,
plasma and other biological fluids.
Introduction
CTGF is a member of an emerging family of regulatory proteins grouped together under
the acronym CCN (CTGF, Cysteine-rich protein (CyR61), and Nephroblastoma
overexpression gene (Nov)). Its overexpression is well described in various fibrotic
disorders including scleroderma, renal and pulmonary fibrosis, inflammatory bowel
disease, and atherosclerosis. CTGF has the ability to affect the ECM metabolism by
directly promoting collagen synthesis and regulating the expression of MMPs and TIMPs.
Its potential role as a therapeutic target in controlling various ocular fibrotic diseases has
been highlighted in recent studies related to corneal scarring,40 ocular cicatricial
pemphigoid, and glaucoma filtration surgery. CTGF gene expression had also been
demonstrated in human trabecular meshwork cells, ciliary body, retinal vascular
endothelial cells, proliferative vitreoretinopathy membranes, choroidal neovascular
membranes, cataractous plaque, corneal scars, tear fluid, and pterygia.
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Wuhan EIAab Science Co.,Ltd.